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10 Regular Prescribed Drugs

A total of 4 billion prescriptions were issued to American patients in 2010. Seventy eight percent of the prescriptions written to American...

A total of 4 billion prescriptions were issued to American patients in 2010. Seventy eight percent of the prescriptions written to Americans in 2010 were for generic drugs. 

The list included unbranded and those still sold under a brand name. In order of quantities of prescriptions – the 10 most prescribed drugs in the U.S. are recorded according to their regular purchases.

Here is the full list of the 10 most prescribed drugs:

1. Hydrocodone (combined with acetaminophen) – a total of 131.2 million prescriptions were written

2. Generic Zocor (simvastatin) – a cholesterol-lowering statin drug: doctors issued 94.1 million prescriptions


3. Lisinopril (include Prinivil and Zestril) – a blood pressure drug: 87.4 million prescriptions for patients

4. Generic Synthroid (levothyroxine sodium) – synthetic thyroid hormone: 70.5 million prescriptions altogether

5. Generic Norvasc (amlodipine besylate) – a blood pressure drug numbering: 57.2 million prescriptions in total

6. Generic Prilosec (omeprazole) – an antacid drug: 53.4 million prescriptions. The figure excludes over the counter sales


7. Azithromycin (brand names include Z-Pak and Zithromax) – an antibiotic: 52.6 million prescriptions were issued

8. Amoxicillin (various brand names) – an antibiotic: 52.3 million prescriptions

9. Generic Glucophage (metformin) – a diabetes drug: 48.3 million prescriptions were written

10. Hydrochlorothiazide (various brand names) – a water pill used to lower blood pressure. A total of 47.8 million prescriptions were issued. – Online Sources



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